KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM12
All Species:
11.82
Human Site:
S755
Identified Species:
26
UniProt:
O43184
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43184
NP_003465.3
909
99542
S755
K
L
R
C
V
R
P
S
R
P
P
R
G
F
Q
Chimpanzee
Pan troglodytes
XP_508106
914
100282
S760
K
L
R
C
V
R
P
S
R
P
P
R
G
F
Q
Rhesus Macaque
Macaca mulatta
XP_001087980
909
99411
S755
K
L
R
C
V
R
P
S
R
P
P
R
G
S
Q
Dog
Lupus familis
XP_546274
909
99674
C739
K
L
R
Q
Q
F
S
C
P
F
R
V
S
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61824
903
98582
S753
K
L
R
C
V
H
P
S
R
T
P
S
G
P
H
Rat
Rattus norvegicus
Q9QYV0
816
88034
W681
H
C
H
C
D
E
G
W
A
P
P
D
C
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
F687
R
Q
P
F
R
C
P
F
K
V
A
Q
K
G
G
Chicken
Gallus gallus
NP_001136322
922
101009
A767
K
L
R
S
V
S
P
A
R
S
S
R
S
S
K
Frog
Xenopus laevis
O42596
935
104143
K776
I
P
Q
G
D
Y
V
K
K
P
G
D
A
D
S
Zebra Danio
Brachydanio rerio
XP_001921148
773
83366
V641
I
Y
Q
P
V
D
S
V
L
P
S
H
S
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999635
1023
111059
N762
T
Y
P
S
S
T
N
N
Y
R
N
Q
E
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
43.7
N.A.
80.3
35.5
N.A.
43.3
71.5
28.3
56.7
N.A.
N.A.
N.A.
N.A.
35.8
Protein Similarity:
100
95.9
97.1
59.4
N.A.
88.1
50.3
N.A.
58
82.4
44.4
65.2
N.A.
N.A.
N.A.
N.A.
51.2
P-Site Identity:
100
100
93.3
20
N.A.
66.6
20
N.A.
6.6
46.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
20
N.A.
66.6
20
N.A.
26.6
60
20
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
10
0
10
0
0
% A
% Cys:
0
10
0
46
0
10
0
10
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
19
10
0
0
0
0
0
19
0
10
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
10
0
10
0
10
0
0
0
19
0
% F
% Gly:
0
0
0
10
0
0
10
0
0
0
10
0
37
10
10
% G
% His:
10
0
10
0
0
10
0
0
0
0
0
10
0
0
10
% H
% Ile:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
55
0
0
0
0
0
0
10
19
0
0
0
10
0
10
% K
% Leu:
0
55
0
0
0
0
0
0
10
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
10
% N
% Pro:
0
10
19
10
0
0
55
0
10
55
46
0
0
10
0
% P
% Gln:
0
10
19
10
10
0
0
0
0
0
0
19
0
10
28
% Q
% Arg:
10
0
55
0
10
28
0
0
46
10
10
37
0
0
19
% R
% Ser:
0
0
0
19
10
10
19
37
0
10
19
10
28
28
10
% S
% Thr:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% T
% Val:
0
0
0
0
55
0
10
10
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _